Basic Fibroblast Growth Factor in Scarless Wound Healing
نویسندگان
چکیده
منابع مشابه
Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice
The stimulatory effect of recombinant basic fibroblast growth factor (bFGF) on wound healing was assessed using healing-impaired (db/db) mice. Full-thickness wounds were made in female diabetic C57BL/KsJ db/db mice, and their normal (db/+) littermates with a punch biopsy instrument. Recombinant bFGF was applied locally to the open wound once a day. The mice were later killed and histological se...
متن کاملRecombinant Basic Fibroblast Growth Factor Stimulates Wound Healing in Healing-impaired dbldb Mice
The stimulatory effect of recombinant basic fibroblast growth factor (bFGF) on wound healing was assessed using healing-impaired (db/db) mice. Full-thickness wounds were made in female diabetic C57BL/Ksj AM mice, and their normal (db/+) littermates with a punch biopsy instrument . Recombinant bFGF was applied locally to the open wound once a day. The mice were later killed and histological sect...
متن کاملAdvances in Scarless Wound Healing
Wound care is a perennial burden for the US healthcare system, costing an estimated $25 billion annually for the treatment of chronic wounds alone [1]. Problems surrounding scarring have also created a $12 billion market annually for treatment [2]. In the 1979 landmark study, Rowlatt et al. reported that human fetal wound healing did not cause scar formation [3]. Animal models were subsequently...
متن کاملEffect of Basic Fibroblast Growth Factor on Achilles Tendon Healing in Rabbit
BACKGROUND Tendon injuries are common and it takes a long time for an injured tendon to heal. Adverse phenomena such as adhesion and rupture are associated with these injuries. Finding a method to reduce the time required for healing whichimproves the final outcome, will lead to decreased frequency and intensity of adverse consequences. This study was designed to investigate the effects ...
متن کاملBasic fibroblast growth factor stimulates corneal endothelial cell growth and endothelial wound healing of human corneas.
PURPOSE To determine the dose response of human recombinant basic fibroblast growth factor (bFGF) on mitogenic activity, and the supplementary role of serum in cultured bovine and human corneal endothelial cells (BCECs, HCECs). To investigate the effect of bFGF on endothelial wound healing of human corneas in vitro. METHODS In cell culture, DNA synthesis was assessed by 3H-thymidine incorpora...
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ژورنال
عنوان ژورنال: Advances in Wound Care
سال: 2013
ISSN: 2162-1918,2162-1934
DOI: 10.1089/wound.2011.0324